Setmelanotide impurity profile
Every named species the index has reported alongside Setmelanotide, how often, at what level, and what its presence implies about the synthesis or the handling. Reporting threshold is 0.05 % area; anything below it is invisible to this page and is silently added to the main peak.
| Named species | ΔRT (min) | Δ mass (Da) | Seen in | Median % area | Max % area |
|---|---|---|---|---|---|
| open-chain (reduced disulfide, +2 Da) | -0.58 | +2.016 | — | not observed | — |
| disulfide-scrambled isomer | +0.34 | mass-identical | — | not observed | — |
| oxidised Trp (+16 Da) | -0.32 | +15.995 | — | not observed | — |
| des-acetyl (−42 Da) | -0.44 | -42.011 | — | not observed | — |
Degradation pathways
Degradants are a handling finding rather than a synthesis finding. A lot that shipped clean and arrived oxidised tells you about the courier, not the chemist.
- disulfide reduction
- Trp oxidation